Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28645487 | 1.00 | TDP1 (0.42) | TDP1DDB1CRBNMMP13MMP1 | |
| SCHEMBL28927692 | 0.71 | TDP1 (0.38) | TDP1DDB1CRBNLMNACYP19A1 | |
| SCHEMBL28650427 | 0.69 | TDP1 (0.39) | TDP1DDB1CRBNMMP13MMP1 | |
| SCHEMBL28650428 | 0.69 | TDP1 (0.39) | TDP1DDB1CRBNMMP13MMP1 | |
| SCHEMBL28645239 | 0.69 | TDP1 (0.44) | TDP1DDB1CRBNMMP13MMP1 | |
| SCHEMBL30823808 | 0.69 | TDP1 (0.41) | TDP1DDB1CRBNMMP13MMP1 | |
| SCHEMBL28650430 | 0.68 | TDP1 (0.43) | TDP1MMP13MMP1KMT2ASMN1; SMN2 | |
| SCHEMBL680920 | 0.67 | DDB1 (0.47) | DDB1CRBNKMT2A | |
| SCHEMBL7354999 | 0.65 | KMT2A (0.51) | TDP1KMT2ASMN1; SMN2NPSR1LMNA | |
| SCHEMBL28926766 | 0.65 | DDB1 (0.45) | DDB1CRBNKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461599-B | Process for preparing piperidone compounds | 南方科技大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-113461599-A | Process for producing piperidone compound | 南方科技大学 | 2021-10-01 | — | — | CN | disclosed |