Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LIG1 | P18858 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30823808 | 0.69 | TDP1 (0.41) | TDP1MMP13MMP1MMP2MMP3 | |
| SCHEMBL28645487 | 0.68 | TDP1 (0.42) | TDP1MMP13MMP1MMP2MMP3 | |
| SCHEMBL28645486 | 0.68 | TDP1 (0.42) | TDP1MMP13MMP1MMP2MMP3 | |
| SCHEMBL28645239 | 0.67 | TDP1 (0.44) | TDP1MMP13MMP1MMP2MMP3 | |
| SCHEMBL28645251 | 0.63 | SLC6A9 (0.39) | TDP1GAAALDH1A1KMT2A | |
| SCHEMBL28927692 | 0.61 | TDP1 (0.38) | TDP1LMNAGAAKDM1ARCOR1 | |
| SCHEMBL8270572 | 0.61 | TDP1 (1.00) | TDP1LMNAGAAALDH1A1MAPT | |
| SCHEMBL1421341 | 0.61 | TDP1 (1.00) | TDP1LMNAGAAALDH1A1MAPT | |
| SCHEMBL29028926 | 0.60 | TDP1 (0.45) | TDP1MMP13MMP1LMNALIG1 | |
| SCHEMBL30823804 | 0.60 | TDP1 (0.42) | TDP1MMP13MMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461599-B | Process for preparing piperidone compounds | 南方科技大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-113461599-A | Process for producing piperidone compound | 南方科技大学 | 2021-10-01 | — | — | CN | disclosed |