Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | LIG1 | P18858 | 1/20 | 0.37 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28926766 | 0.83 | DDB1 (0.45) | LMNAKDM1ADDB1CRBN | |
| SCHEMBL28653281 | 0.81 | DDB1 (0.52) | LMNAHSD11B1MMP13MMP1ALDH1A1 | |
| SCHEMBL28653243 | 0.76 | MMP13 (0.43) | TDP1LMNAMMP13ALDH1A1DDB1 | |
| SCHEMBL28647492 | 0.75 | ALDH1A1 (0.41) | TDP1LMNAALDH1A1KDM1ARCOR1 | |
| SCHEMBL30823804 | 0.73 | TDP1 (0.42) | TDP1NPSR1LMNALIG1HSD11B1 | |
| SCHEMBL30823799 | 0.71 | DDB1 (0.56) | LMNAHSD11B1ALDH1A1KDM1ARCOR1 | |
| SCHEMBL28644757 | 0.71 | DDB1 (0.56) | LMNAHSD11B1ALDH1A1KDM1ARCOR1 | |
| SCHEMBL28645487 | 0.69 | TDP1 (0.42) | TDP1NPSR1LMNAMMP13MMP1 | |
| SCHEMBL17055134 | 0.67 | CYP19A1 (0.53) | CYP19A1DDB1CRBN | |
| SCHEMBL17055133 | 0.67 | LMNA (0.43) | LMNALIG1KDM1ARCOR1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461599-B | Process for preparing piperidone compounds | 南方科技大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-113461599-A | Process for producing piperidone compound | 南方科技大学 | 2021-10-01 | — | — | CN | disclosed |