Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 4/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | F11 | P03951 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16650743 | 0.84 | LPL (0.33) | LPLLIPGIDO1TDO2BACE1 | |
| SCHEMBL22230214 | 0.82 | AAK1 (0.34) | LPLLIPGBACE1F11FFAR1 | |
| SCHEMBL22655363 | 0.81 | LPL (0.36) | LPLLIPGROCK1BACE1F11 | |
| SCHEMBL16650516 | 0.80 | LPL (0.40) | LPLLIPGROCK1IDO1TDO2 | |
| SCHEMBL22655301 | 0.80 | CSF1R (0.38) | LPLLIPGBACE1FFAR1CA1 | |
| SCHEMBL31752740 | 0.77 | LPL (0.37) | LPLLIPGROCK1IDO1TDO2 | |
| SCHEMBL505914 | 0.74 | LPL (0.41) | LPLLIPGBACE1F11FFAR1 | |
| SCHEMBL28647197 | 0.71 | KDM4E (0.30) | — | |
| SCHEMBL878145 | 0.70 | F11 (0.34) | LIPGBACE1F11F2PRSS1 | |
| SCHEMBL1106436 | 0.70 | BRD4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109293652-B | Substituted thiazole derivative and application thereof | 四川科伦博泰生物医药股份有限公司 | 2021-10-22 | — | — | CN | disclosed |