SCHEMBL2864589

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2872606	0.85	SMN1; SMN2 (0.46)	HPGDALDH1A1RAB9AGAANPC1
	SCHEMBL2861469	0.84	CDK4 (0.48)	HPGDALDH1A1MAPK1KDM4ELMNA
	SCHEMBL4335941	0.78	MAPT (0.49)	HPGDALDH1A1MAPK1KDM4ELMNA
	SCHEMBL4341432	0.78	ALDH1A1 (0.47)	HPGDALDH1A1MAPK1KDM4ELMNA
	SCHEMBL4340978	0.78	ALDH1A1 (0.46)	HPGDALDH1A1MAPK1KDM4ELMNA
	SCHEMBL2864411	0.76	MAPK10 (0.46)	MAPK1MAPK10MAPKAPK2
	SCHEMBL4334072	0.76	HPGD (0.47)	HPGDALDH1A1MAPK1KDM4ERAB9A
	SCHEMBL2862326	0.75	KDM4E (0.46)	HPGDALDH1A1KDM4EMAPK10MAPKAPK2
	SCHEMBL2870292	0.75	MAPKAPK2 (0.48)	MAPK10MAPKAPK2
	SCHEMBL6753821	0.75	MAPKAPK2 (0.41)	MAPK1RAB9ANPC1MAPK10MAPKAPK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.