SCHEMBL4335941

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4340978	0.86	ALDH1A1 (0.46)	MAPTSMN1; SMN2HPGDHSD17B10ALDH1A1
	SCHEMBL4341021	0.85	MAPT (0.49)	MAPTSMN1; SMN2TP53HPGDHSD17B10
	SCHEMBL4334979	0.84	MAPT (0.44)	MAPTSMN1; SMN2TP53HPGDHSD17B10
	SCHEMBL2864411	0.83	MAPK10 (0.46)	MAPK10KDRMAPK1
	SCHEMBL2862326	0.81	KDM4E (0.46)	HPGDHSD17B10ALDH1A1MAPK10KDM4E
	SCHEMBL2870547	0.80	RAB9A (0.48)	SMN1; SMN2ALDH1A1RAB9AMAPK10KDR
	SCHEMBL4338881	0.80	KDM4E (0.53)	MAPTSMN1; SMN2HPGDHSD17B10ALDH1A1
	SCHEMBL4336833	0.79	MAPK10 (0.40)	RAB9AMAPK10NPC1MAPK1
	SCHEMBL4329239	0.79	MAPK1 (0.45)	MAPK10MAPK1
	SCHEMBL2864589	0.78	HPGD (0.44)	MAPTSMN1; SMN2TP53HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.