Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21758682 | 0.91 | LTA4H (0.46) | HDAC3HDAC1HDAC2HDAC8HTT | |
| SCHEMBL29151949 | 0.85 | TDP1 (0.50) | HTTLTA4HMEN1KMT2AL3MBTL1 | |
| SCHEMBL14350236 | 0.83 | HTT (0.49) | KDM4AKDM4CHDAC3HDAC1HDAC2 | |
| SCHEMBL14350197 | 0.79 | KDM4A (0.50) | KDM4AKDM4CHDAC3HDAC1HDAC2 | |
| SCHEMBL17540988 | 0.78 | ALOX5 (0.54) | MAPK1SMN1; SMN2HTTLTA4HMEN1 | |
| SCHEMBL14350209 | 0.77 | KDM4A (0.52) | KDM4AKDM4CHDAC3HDAC1HDAC2 | |
| SCHEMBL14350210 | 0.77 | KDM4A (0.52) | KDM4AKDM4CHDAC3HDAC1HDAC2 | |
| SCHEMBL14350200 | 0.77 | KDM4A (0.52) | KDM4AKDM4CHDAC3HDAC1HDAC2 | |
| SCHEMBL14350181 | 0.77 | KDM4A (0.52) | KDM4AKDM4CHDAC3HDAC1HDAC2 | |
| SCHEMBL14350189 | 0.76 | KMT2A (0.51) | KDM4AKDM4CHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112739698-A | Tetrahydropyrimidine derivatives as AHR modulators | 捷豹治疗有限公司 | 2021-04-30 | — | — | CN | disclosed |