Flufenacet

Flufenacet

SCHEMBL28646237

CC(C)N(C(=O)COc1nnc(C(F)(F)F)s1)c1ccc(F)cc1.NC(=O)CF

nearest known ligand 0.88

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
ALDH1A1 P00352 2/20 0.31
BACE1 P56817 1/20 0.31
ATM Q13315 1/20 0.31
TACR1 P25103 1/20 0.31
CCKAR P32238 1/20 0.30
CCKBR P32239 1/20 0.30
MC4R P32245 2/20 0.30
MC1R Q01726 2/20 0.30
TSHR P16473 2/20 0.30
HSD17B10 Q99714 2/20 0.30
LMNA P02545 2/20 0.30
HTT P42858 1/20 0.30
MAPT P10636 1/20 0.30
TP53 P04637 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flufenacet SCHEMBL28200397 0.94 MLYCD (0.32) MLYCDMEN1KMT2AALDH1A1BACE1
Flufenacet SCHEMBL4897219 0.94 MLYCD (0.34) MLYCDMEN1KMT2AALDH1A1BACE1
Flufenacet SCHEMBL116467 0.94 MLYCD (0.34) MLYCDMEN1KMT2AALDH1A1BACE1
Flufenacet SCHEMBL19838480 0.93 MLYCD (0.33) MLYCDMEN1KMT2AALDH1A1BACE1
Flufenacet SCHEMBL28095406 0.93 MLYCD (0.34) MLYCDMEN1KMT2AALDH1A1BACE1
Flufenacet SCHEMBL28743320 0.93 MLYCD (0.34) MLYCDMEN1KMT2AALDH1A1BACE1
Flufenacet SCHEMBL7205592 0.93 MLYCD (0.34) MLYCDMEN1KMT2AALDH1A1BACE1
Flufenacet SCHEMBL26967734 0.91 MLYCD (0.35) MLYCDMEN1KMT2AALDH1A1BACE1
Flufenacet SCHEMBL28619978 0.88 BACE1 (0.35) MLYCDMEN1KMT2AALDH1A1BACE1
Flufenacet SCHEMBL18115274 0.87 MEN1 (0.32) MLYCDMEN1KMT2AALDH1A1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110997838-B Silicone-polyether copolymers, sealants including silicone-polyether copolymers, and related methods 美国陶氏有机硅公司 2021-10-01 CN disclosed