Flufenacet

Flufenacet

SCHEMBL18115274

CC(C)N(C(=O)COc1nnc(C(F)(F)F)s1)c1ccc(F)cc1.C[n+]1ccc(-c2cc[n+](C)cc2)cc1

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ALDH1A1 P00352 1/20 0.32
ATM Q13315 1/20 0.32
MC4R P32245 3/20 0.31
MC1R Q01726 3/20 0.31
MLYCD O95822 1/20 0.31
BACE1 P56817 1/20 0.30
TACR1 P25103 1/20 0.30
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flufenacet SCHEMBL116467 0.92 MLYCD (0.34) MEN1KMT2AALDH1A1ATMMC4R
Flufenacet SCHEMBL4897219 0.92 MLYCD (0.34) MEN1KMT2AALDH1A1ATMMC4R
Flufenacet SCHEMBL28095406 0.91 MLYCD (0.34) MEN1KMT2AALDH1A1ATMMC4R
Flufenacet SCHEMBL28743320 0.91 MLYCD (0.34) MEN1KMT2AALDH1A1ATMMC4R
Flufenacet SCHEMBL7205592 0.91 MLYCD (0.34) MEN1KMT2AALDH1A1ATMMC4R
Flufenacet SCHEMBL26967734 0.89 MLYCD (0.35) MEN1KMT2AALDH1A1ATMMC4R
Flufenacet SCHEMBL19838480 0.89 MLYCD (0.33) MEN1KMT2AALDH1A1ATMMC4R
Flufenacet SCHEMBL28200397 0.88 MLYCD (0.32) MEN1KMT2AALDH1A1ATMMC4R
Flufenacet SCHEMBL28646237 0.87 MLYCD (0.31) MEN1KMT2AALDH1A1ATMMC4R
SCHEMBL5718493 0.84 ALDH1A1 (0.34) MEN1KMT2AALDH1A1ATMMC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3280260-A1 HERBICIDAL MIXTURES Syngenta Participations AG (CH) 2018-02-14 EP disclosed
EP-3277089-A1 HERBICIDAL MIXTURES Syngenta Participations AG (CH) 2018-02-07 EP disclosed
WO-2016162265-A1 HERBICIDAL MIXTURES SYNGENTA PARTICIPATIONS AG (CH) 2016-10-13 WO disclosed
WO-2016156241-A1 HERBICIDAL MIXTURES SYNGENTA PARTICIPATIONS AG (CH) 2016-10-06 WO disclosed