Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 19/20 | 0.51 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.40 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27959304 | 0.88 | MAP3K5 (0.52) | MAP3K5 | |
| SCHEMBL28648093 | 0.88 | MAP3K5 (0.52) | MAP3K5MLLT3MLLT1 | |
| SCHEMBL28643803 | 0.84 | MAP3K5 (0.53) | MAP3K5MLLT3MLLT1 | |
| SCHEMBL27959287 | 0.83 | KMO (0.49) | MAP3K5MLLT3MLLT1 | |
| SCHEMBL27959298 | 0.82 | KMO (0.51) | MAP3K5MLLT3MLLT1 | |
| SCHEMBL28643386 | 0.81 | MAP3K5 (0.38) | MAP3K5 | |
| SCHEMBL28643807 | 0.81 | MAP3K5 (0.41) | MAP3K5 | |
| SCHEMBL20750911 | 0.79 | MAP3K5 (0.41) | MAP3K5 | |
| SCHEMBL28660342 | 0.79 | KDM4C (0.43) | MAP3K5 | |
| SCHEMBL28668610 | 0.79 | MAP3K5 (0.53) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109400625-B | Fused bicyclic compound and application thereof in medicine | 广东东阳光药业有限公司 | 2021-11-12 | — | — | CN | disclosed |