Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.42 |
| ▸ | CES1 | P23141 | 10/20 | 0.42 |
| ▸ | CES2 | O00748 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19409848 | 1.00 | FAAH (0.42) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL29286403 | 0.92 | FAAH (0.50) | FAAHCES1MEN1CYP1A2KMT2A | |
| Sulfuric Acid SCHEMBL29078533 | 0.91 | FAAH (0.47) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL455073 | 0.87 | FAAH (0.53) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL2410991 | 0.87 | FAAH (0.53) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL28363537 | 0.86 | FAAH (0.46) | FAAHCES1CES2MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL16538159 | 0.85 | FAAH (0.52) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL28498503 | 0.85 | FAAH (0.40) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL28334153 | 0.85 | FAAH (0.40) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL28336601 | 0.80 | FAAH (0.43) | FAAHCES1CES2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105828882-B | Packaging article comprising an envelope and an anhydrous dye composition comprising a direct dye, use thereof and process for dyeing keratin fibres | 莱雅公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-114901249-A | Composition for conditioning keratin materials | 莱雅公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-105828884-B | Packaging article comprising an envelope and an anhydrous dye composition comprising an oxidation dye, use thereof and process for dyeing keratin fibres | 莱雅公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-108158833-B | Cosmetic composition comprising a specific zinc salt and an aminosilicone | 莱雅公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-107412005-B | Composition for dyeing keratin fibers | 莱雅公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-107750153-B | Compositions and methods for treating hair | 欧莱雅 | 2021-09-03 | — | — | CN | disclosed |