Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG known ✓ | P37231 | 5/20 | 0.43 |
| ▸ | HDAC11 known ✓ | Q96DB2 | 4/20 | 0.43 |
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.43 |
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.43 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 8/20 | 0.52 |
| ▸ | CES1 | P23141 | 8/20 | 0.52 |
| ▸ | CES2 | O00748 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 5/20 | 0.43 |
| ▸ | PPARA | Q07869 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2410991 | 0.98 | FAAH (0.53) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL455073 | 0.98 | FAAH (0.53) | FAAHCES1CES2MEN1KMT2A | |
| Sulfuric Acid SCHEMBL29078533 | 0.91 | FAAH (0.47) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL27473405 | 0.86 | FAAH (0.57) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL19409848 | 0.85 | FAAH (0.42) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL28646473 | 0.85 | FAAH (0.42) | FAAHCES1CES2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30656537 | 0.82 | FAAH (0.57) | FAAHCES1CES2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL17294134 | 0.81 | FAAH (0.48) | FAAHCES1CES2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL341117 | 0.80 | FAAH (0.55) | FAAHCES1CES2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL219232 | 0.79 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041581-B1 | HAIR CARE COMPOSITION COMPRISING AMINO SILICONE, FATTY ALCOHOL AND PARAFFIN OIL | OREAL (FR) | 2020-04-01 | — | — | EP | claimed |
| EP-3041581-A1 | HAIR CARE COMPOSITION COMPRISING AMINO SILICONE, FATTY ALCOHOL AND PARAFFIN OIL | L'OREAL (FR) | 2016-07-13 | — | — | EP | claimed |
| WO-2015027302-A1 | HAIR CARE COMPOSITION COMPRISING AMINO SILICONE, FATTY ALCOHOL AND PARAFFIN OIL | L'OREAL (FR) | 2015-03-05 | — | — | WO | claimed |
| WO-2024197632-A1 | COMPOSITION FOR CLEANSING THE SKIN | L'OREAL (FR) | 2024-10-03 | — | — | WO | disclosed |
| US-20240189207-A1 | COMPOSITION FOR CLEANSING AND/OR REMOVING MAKEUPS FROM KERATIN MATERIALS | L'OREAL (FR) | 2024-06-13 | — | — | US | disclosed |
| EP-4358930-A1 | COMPOSITION FOR CLEANSING AND/OR REMOVING MAKEUPS FROM KERATIN MATERIALS | L'OREAL (FR) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022266947-A1 | COMPOSITION FOR CLEANSING AND/OR REMOVING MAKEUPS FROM KERATIN MATERIALS | L'OREAL (FR) | 2022-12-29 | — | — | WO | disclosed |
| US-10653611-B2 | Hair care composition comprising amino silicone, fatty alcohol and paraffin oil | L'OREAL (FR) | 2020-05-19 | — | — | US | disclosed |
| EP-3041581-B1 | HAIR CARE COMPOSITION COMPRISING AMINO SILICONE, FATTY ALCOHOL AND PARAFFIN OIL | OREAL (FR) | 2020-04-01 | — | — | EP | disclosed |
| US-20160206547-A1 | HAIR CARE COMPOSITION COMPRISING AMINO SILICONE, FATTY ALCOHOL AND PARAFFIN OIL | L'OREAL (FR) | 2016-07-21 | — | — | US | disclosed |
| EP-3041581-A1 | HAIR CARE COMPOSITION COMPRISING AMINO SILICONE, FATTY ALCOHOL AND PARAFFIN OIL | L'OREAL (FR) | 2016-07-13 | — | — | EP | disclosed |
| WO-2016066812-A1 | TRANSPARENT LIQUID SOAP | L'OREAL (FR) | 2016-05-06 | — | — | WO | disclosed |
| WO-2015027302-A1 | HAIR CARE COMPOSITION COMPRISING AMINO SILICONE, FATTY ALCOHOL AND PARAFFIN OIL | L'OREAL (FR) | 2015-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160206547-A1 | HAIR CARE COMPOSITION COMPRISING AMINO SILICONE, FATTY ALCOHOL AND PARAFFIN OIL | KRT18, CUTA, AADAT | PPARG 622/4885HDAC11 1438/4885ESR1 3290/4885 |
| US-10653611-B2 | Hair care composition comprising amino silicone, fatty alcohol and paraffin oil | KRT18, CUTA, AADAT | PPARG 622/4885HDAC11 1438/4885ESR1 3290/4885 |
| US-20240189207-A1 | COMPOSITION FOR CLEANSING AND/OR REMOVING MAKEUPS FROM KERATIN MATERIALS | KRT18, CUTA, DSG1 | PPARG 2575/4885HDAC11 2563/4885ESR1 4084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.