SCHEMBL2864682

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22446034	0.84	MAP2K4 (0.59)	CDK2MAPK9MAPK10MAP2K4AURKA
	SCHEMBL2864582	0.83	CDK2 (0.47)	MAPKAPK2CDK4CCNA2CCND1CDK2
	SCHEMBL4378603	0.83	MAPKAPK2 (0.45)	MAPKAPK2CDK4CCNA2CCND1CDK2
	SCHEMBL2860960	0.80	CDK4 (0.45)	MAPKAPK2CDK4CCNA2CCND1CDK2
	SCHEMBL2859865	0.80	MAP2K4 (0.51)	MAPKAPK2MAP2K4AURKAADORA2A
	SCHEMBL2862300	0.79	MEN1 (0.47)	MAPKAPK2CDK4CCNA2CCND1CDK2
	SCHEMBL2863193	0.77	MAPKAPK2 (0.46)	MAPKAPK2CDK4CCNA2CCND1CDK2
	SCHEMBL2861529	0.76	MAPKAPK2 (0.53)	MAPKAPK2CCNA2CDK2MAPK10IKBKB
	SCHEMBL13198226	0.76	SRC (0.49)	KDRADORA2AADORA1CYP1A2PIK3CD
	SCHEMBL13927625	0.76	IDO1 (0.63)	MAPKAPK2CDK4CCNA2CCND1CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.