Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 4/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | GRK2 | P25098 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28657657 | 0.77 | GRIN2D (0.60) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL22431375 | 0.69 | HTT (0.36) | NPSR1MAPTGRK2POLBLMNA | |
| Acetic Acid SCHEMBL17395931 | 0.68 | KDM4E (0.39) | MAPTGRK2POLBLMNACYP1A2 | |
| Acetic Acid SCHEMBL17395930 | 0.68 | KDM4E (0.39) | MAPTGRK2POLBLMNACYP1A2 | |
| SCHEMBL4637840 | 0.66 | GAA (0.42) | TSHRL3MBTL1KDM4E | |
| SCHEMBL4637844 | 0.66 | GAA (0.42) | TSHRL3MBTL1KDM4E | |
| SCHEMBL15157563 | 0.66 | CCNC (0.41) | NPSR1MAPTCA1CA2LMNA | |
| SCHEMBL15875058 | 0.65 | KMT2A (0.39) | NPSR1MAPTPOLBLMNAL3MBTL1 | |
| SCHEMBL15875061 | 0.65 | KMT2A (0.39) | NPSR1MAPTPOLBLMNAL3MBTL1 | |
| SCHEMBL18474178 | 0.64 | MEN1 (0.39) | MAPTGRK2LMNAL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074752-B | Therapeutic use of benzylidene guanidine derivatives for the treatment of protein conformation disorders | 英费列特斯生命科学公司 | 2021-10-26 | — | — | CN | disclosed |