Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 11/20 | 0.60 |
| ▸ | GRIN3B | O60391 | 11/20 | 0.60 |
| ▸ | GRIN1 | Q05586 | 11/20 | 0.60 |
| ▸ | GRIN2A | Q12879 | 11/20 | 0.60 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.60 |
| ▸ | GRIN2C | Q14957 | 11/20 | 0.60 |
| ▸ | GRIN3A | Q8TCU5 | 11/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | PPP1R15A | O75807 | 1/20 | 0.53 |
| ▸ | MELK | Q14680 | 1/20 | 0.53 |
| ▸ | PPP1R15B | Q5SWA1 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28647145 | 0.77 | GRIN2D (0.37) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL4637844 | 0.77 | GAA (0.42) | L3MBTL1KMT2ATSHR | |
| SCHEMBL4637840 | 0.77 | GAA (0.42) | L3MBTL1KMT2ATSHR | |
| SCHEMBL29445212 | 0.75 | GRIN2D (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL15884162 | 0.75 | GRIN2D (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL15875061 | 0.73 | KMT2A (0.39) | NPSR1MAPTL3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL15875058 | 0.73 | KMT2A (0.39) | NPSR1MAPTL3MBTL1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL5703155 | 0.71 | GRIN2D (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL22431375 | 0.71 | HTT (0.36) | NPSR1MAPTL3MBTL1KMT2ANPC1 | |
| SCHEMBL4637787 | 0.70 | GAA (0.39) | NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074752-B | Therapeutic use of benzylidene guanidine derivatives for the treatment of protein conformation disorders | 英费列特斯生命科学公司 | 2021-10-26 | — | — | CN | disclosed |