Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4637840 | 1.00 | GAA (0.42) | GAACCNT1CDK9HASPINHTT | |
| SCHEMBL1982834 | 0.86 | CCNT1 (0.43) | GAACCNT1CDK9HASPINHTT | |
| SCHEMBL1982833 | 0.86 | CCNT1 (0.43) | GAACCNT1CDK9HASPINHTT | |
| SCHEMBL25320343 | 0.78 | CCNT1 (0.43) | GAACCNT1CDK9HASPINHTT | |
| SCHEMBL4637787 | 0.77 | GAA (0.39) | GAAHTTCDK5CDK5R1GSK3B | |
| SCHEMBL28657657 | 0.77 | GRIN2D (0.60) | TSHRKMT2AL3MBTL1 | |
| SCHEMBL15741494 | 0.76 | — | — | |
| SCHEMBL6069581 | 0.76 | CCNT1 (0.42) | GAACCNT1CDK9HASPINHTT | |
| SCHEMBL6069584 | 0.76 | CCNT1 (0.42) | GAACCNT1CDK9HASPINHTT | |
| SCHEMBL4764878 | 0.76 | CCNC (0.50) | GAACCNT1CDK9HASPINHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501808-B1 | TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-07-02 | — | — | EP | disclosed |
| CN-1313450-C | Tachykinin receptor antagonists | LILLY CO ELI (US) | 2007-05-02 | — | — | CN | disclosed |