Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28647186

CC(O)COC(=O)/C=C\C(=O)O.N

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 13/20 0.55
TSHR P16473 4/20 0.44
MAPT P10636 1/20 0.38
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
ATM Q13315 1/20 0.36
TP53 P04637 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
EGLN3 Q9H6Z9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL182315 0.98 HCAR2 (0.57) HCAR2TSHRMAPTALDH1A1GAA
SCHEMBL2808163 0.98 HCAR2 (0.57) HCAR2TSHRMAPTALDH1A1GAA
SCHEMBL182314 0.98 HCAR2 (0.57) HCAR2TSHRMAPTALDH1A1GAA
SCHEMBL4444141 0.89 TSHR (0.52) HCAR2TSHRMAPTALDH1A1ATM
SCHEMBL2808160 0.89 TSHR (0.52) HCAR2TSHRMAPTALDH1A1ATM
SCHEMBL2465097 0.89 TSHR (0.52) HCAR2TSHRMAPTALDH1A1ATM
Acrylic Acid SCHEMBL28316625 0.88 TSHR (0.53) HCAR2TSHRMAPTALDH1A1ATM
Fumaric Acid SCHEMBL11785039 0.86 TSHR (0.62) HCAR2TSHRMAPTALDH1A1GAA
Maleic Acid SCHEMBL3330980 0.86 TSHR (0.62) HCAR2TSHRMAPTALDH1A1GAA
SCHEMBL6931716 0.85 HCAR2 (0.48) HCAR2TSHRALDH1A1GAAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109476803-B Amine compositions useful for making polyurethane foams 赢创运营有限公司 2022-04-12 CN claimed
CN-109476803-B Amine compositions useful for making polyurethane foams 赢创运营有限公司 2022-04-12 CN disclosed
CN-107922564-B Trimerization catalysts from sterically hindered salts and tertiary amines having isocyanate-reactive groups 赢创运营有限公司 2021-10-19 CN disclosed