Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.45 |
| ▸ | SKP1 | P63208 | 1/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 7/20 | 0.44 |
| ▸ | ACACA | Q13085 | 7/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | EEF2K | O00418 | 1/20 | 0.41 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28926895 | 0.95 | CKS1B (0.49) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL25080904 | 0.88 | ACACB (0.47) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL12284231 | 0.85 | SUV39H2 (0.48) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL28647151 | 0.82 | DRD2 (0.38) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL8214675 | 0.82 | CKS1B (0.49) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL4288052 | 0.82 | ACACB (0.47) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL4288054 | 0.82 | ACACB (0.47) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL16896516 | 0.81 | CKS1B (0.51) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL7093978 | 0.81 | CKS1B (0.52) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL16896437 | 0.80 | CKS1B (0.48) | CKS1BSKP1SKP2ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527298-B | Macrocyclic lactam derivatives, preparation method and application thereof | 浙江海正药业股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-113527298-A | Macrocyclic lactam derivative, preparation method and application thereof | 浙江海正药业股份有限公司 | 2021-10-22 | — | — | CN | disclosed |