Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 6/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28926895 | 0.85 | CKS1B (0.49) | DRD2ACACBACACACKS1BSKP1 | |
| SCHEMBL28642829 | 0.84 | RORC (0.34) | DRD2GPR119RORCACACBCDK9 | |
| SCHEMBL28642826 | 0.84 | RORC (0.34) | DRD2GPR119RORCACACBCDK9 | |
| SCHEMBL28662653 | 0.83 | GPR119 (0.39) | DRD2GPR119RORCACACBACACA | |
| SCHEMBL28662652 | 0.83 | GPR119 (0.39) | DRD2GPR119RORCACACBACACA | |
| SCHEMBL28648284 | 0.82 | CKS1B (0.45) | DRD2RORCACACBACACACKS1B | |
| SCHEMBL28642831 | 0.79 | ACACB (0.35) | DRD2RORCACACBACACA | |
| SCHEMBL28642843 | 0.78 | GPR119 (0.35) | DRD2GPR119RORCACACBCCNT1 | |
| SCHEMBL28642845 | 0.78 | GPR119 (0.35) | DRD2GPR119RORCACACBCCNT1 | |
| SCHEMBL28642846 | 0.78 | GPR119 (0.35) | DRD2GPR119RORCACACBCCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527298-A | Macrocyclic lactam derivative, preparation method and application thereof | 浙江海正药业股份有限公司 | 2021-10-22 | — | — | CN | disclosed |