Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 known ✓ | P35367 | 2/20 | 0.50 |
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 known ✓ | P08588 | 1/20 | 0.45 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.45 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.45 |
| ▸ | ADRA1D known ✓ | P25100 | 1/20 | 0.45 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3179795 | 0.88 | HRH1 (0.62) | HRH1BCAT2LMNAKDM4ERIPK1 | |
| SCHEMBL42066 | 0.88 | HRH1 (0.62) | HRH1BCAT2LMNAKDM4ERIPK1 | |
| SCHEMBL232834 | 0.88 | HRH1 (0.62) | HRH1BCAT2LMNAKDM4ERIPK1 | |
| Hydrochloric Acid SCHEMBL4374172 | 0.86 | HRH1 (0.60) | HRH1BCAT2LMNAKDM4ETDP1 | |
| SCHEMBL27928248 | 0.86 | HRH1 (0.60) | HRH1BCAT2LMNAKDM4ERIPK1 | |
| Hydrochloric Acid SCHEMBL16032107 | 0.86 | HRH1 (0.60) | HRH1BCAT2LMNAKDM4ETDP1 | |
| Bromide SCHEMBL28648396 | 0.86 | HRH1 (0.60) | HRH1BCAT2LMNAKDM4ERIPK1 | |
| SCHEMBL7417534 | 0.78 | HRH1 (0.68) | HRH1BCAT2LMNAKDM4ERIPK1 | |
| SCHEMBL4281797 | 0.78 | HRH1 (0.68) | HRH1BCAT2LMNAKDM4ERIPK1 | |
| SCHEMBL7373079 | 0.76 | HRH1 (0.59) | HRH1BCAT2LMNAKDM4ERIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418564-A1 | Effervescent cold or sinus allergy medicine composition having reduced sodium content | BAYER AG (DE) | 1991-03-27 | — | — | EP | disclosed |