Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912570 | 0.84 | SMN1; SMN2 (0.82) | SMN1; SMN2L3MBTL1KMT2AMEN1NPC1 | |
| SCHEMBL20269915 | 0.83 | LMNA (0.67) | SMN1; SMN2KMT2AMEN1LMNAMAPT | |
| SCHEMBL28648931 | 0.82 | KMT2A (0.65) | SMN1; SMN2KMT2AMAPTALDH1A1EPHX2 | |
| SCHEMBL28646195 | 0.82 | HPGD (0.72) | KMT2ALMNAMAPTTP53KDM4E | |
| SCHEMBL3590191 | 0.82 | SMN1; SMN2 (0.73) | SMN1; SMN2L3MBTL1KMT2AMEN1NPC1 | |
| SCHEMBL14531874 | 0.82 | SMN1; SMN2 (0.73) | SMN1; SMN2L3MBTL1KMT2AMEN1NPC1 | |
| SCHEMBL95008 | 0.82 | SMN1; SMN2 (0.73) | SMN1; SMN2L3MBTL1KMT2AMEN1NPC1 | |
| SCHEMBL13947384 | 0.82 | SMN1; SMN2 (0.73) | SMN1; SMN2L3MBTL1KMT2AMEN1NPC1 | |
| SCHEMBL3034646 | 0.79 | SMN1; SMN2 (0.83) | SMN1; SMN2L3MBTL1KMT2AMEN1NPC1 | |
| SCHEMBL28648368 | 0.79 | EPHX2 (0.68) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026028-B | Treatment of diabetes and metabolic syndrome with novel dual modulators of soluble epoxide hydrolase and peroxisome proliferator-activated receptors | 威斯康星州医药大学股份有限公司 | 2021-11-09 | — | — | CN | disclosed |