Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21885839 | 0.79 | CYP1A2 (0.44) | HSD17B10TSHRALDH1A1RAB9ANPC1 | |
| SCHEMBL21826830 | 0.79 | CYP1A2 (0.44) | HSD17B10TSHRALDH1A1RAB9ANPC1 | |
| SCHEMBL9467587 | 0.73 | HPGD (0.39) | HSD17B10TSHRALDH1A1RAB9ANPC1 | |
| SCHEMBL21885843 | 0.73 | APLNR (0.31) | — | |
| SCHEMBL21826838 | 0.73 | APLNR (0.31) | — | |
| SCHEMBL21886048 | 0.68 | CA12 (0.31) | — | |
| SCHEMBL21826873 | 0.68 | CA12 (0.31) | — | |
| SCHEMBL9626734 | 0.68 | HPGD (0.39) | HSD17B10TSHRALDH1A1HPGDKDM4C | |
| SCHEMBL16831456 | 0.67 | MEN1 (0.31) | RAB9ANPC1KDM4CMEN1KMT2A | |
| SCHEMBL10579376 | 0.66 | KDM4C (0.39) | HSD17B10TSHRALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113490668-A | Compounds and compositions for treating diseases associated with APJ receptor activity | 安娜普尔纳生物股份有限公司 | 2021-10-08 | — | — | CN | disclosed |