Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDE8B | O95263 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27032120 | 0.79 | KDM4C (0.38) | KDM4CTSHRMEN1KMT2ASLC6A3 | |
| SCHEMBL27133765 | 0.79 | KDM4C (0.38) | KDM4CTSHRMEN1KMT2ASLC6A3 | |
| SCHEMBL7050550 | 0.78 | SIGMAR1 (0.39) | HPGDKDM4CMAOAMEN1KMT2A | |
| SCHEMBL9628663 | 0.75 | KMT2A (0.39) | ALDH1A1MEN1KMT2ASLC6A3MAPT | |
| SCHEMBL27032027 | 0.75 | KDM4C (0.35) | HPGDKDM4CMEN1KMT2AL3MBTL1 | |
| SCHEMBL27131274 | 0.75 | KDM4C (0.35) | HPGDKDM4CMEN1KMT2AL3MBTL1 | |
| Bromide SCHEMBL23387051 | 0.74 | CHRNA7 (0.36) | KDM4CMEN1KMT2ASLC6A3 | |
| SCHEMBL27032595 | 0.74 | KDM4C (0.35) | HPGDKDM4CMEN1KMT2ASLC6A3 | |
| SCHEMBL27032302 | 0.74 | KDM4C (0.35) | HPGDKDM4CMEN1KMT2ASLC6A3 | |
| SCHEMBL27131754 | 0.74 | KDM4C (0.35) | HPGDKDM4CMEN1KMT2ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081152-A | AZULENE DERIVATIVES AS THROMBOXANE A2 AND PROSTAGLANDIN ENDOPEROXIDE RECEPTOR ANTAGONIST | KOTOBUKI SEIYAKU CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |