Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.40 |
| ▸ | LPL | P06858 | 6/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.37 |
| ▸ | PDE4A | P27815 | 4/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17474563 | 0.89 | DGAT1 (0.54) | DGAT1LIPGLPLEGFRMAPT | |
| SCHEMBL182480 | 0.85 | DGAT1 (0.51) | DGAT1LIPGLPLEGFRPDE4B | |
| SCHEMBL27345419 | 0.85 | HIF1A (0.39) | DGAT1LIPGLPLEGFRMAPT | |
| SCHEMBL24058035 | 0.83 | DGAT1 (0.51) | DGAT1LIPGLPLEGFRMAPT | |
| SCHEMBL15884409 | 0.83 | EGFR (0.52) | DGAT1LIPGLPLEGFR | |
| SCHEMBL21823354 | 0.81 | LPL (0.41) | DGAT1LIPGLPLPDE4BPDE4D | |
| SCHEMBL3767677 | 0.81 | DGAT1 (0.52) | DGAT1LIPGLPLEGFRMAPT | |
| SCHEMBL31748489 | 0.81 | DGAT1 (0.52) | DGAT1LIPGLPLEGFRMAPT | |
| SCHEMBL31065363 | 0.81 | DGAT1 (0.47) | DGAT1LIPGLPLEGFRMAPT | |
| SCHEMBL3767557 | 0.81 | DGAT1 (0.47) | DGAT1LIPGLPLEGFRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563244-A | Substituted aza five-membered ring compound and application thereof in medicine | 广东东阳光药业有限公司 | 2021-10-29 | — | — | CN | disclosed |