Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 6/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28663881 | 1.00 | MEN1 (0.42) | MEN1ALDH1A1CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL28665563 | 0.79 | ALDH1A1 (0.34) | MEN1ALDH1A1CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL28653823 | 0.79 | ALDH1A1 (0.34) | MEN1ALDH1A1CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL481729 | 0.70 | MTOR (0.51) | — | |
| SCHEMBL4961332 | 0.68 | BRD4 (0.40) | MEN1ALDH1A1KMT2ASMN1; SMN2FEN1 | |
| SCHEMBL3595224 | 0.68 | CCR2 (0.55) | MEN1ALDH1A1KMT2ACCR2KCNH2 | |
| SCHEMBL3595227 | 0.68 | CCR2 (0.55) | MEN1ALDH1A1KMT2ACCR2KCNH2 | |
| SCHEMBL6224523 | 0.68 | ALDH1A1 (0.56) | MEN1ALDH1A1CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL3996994 | 0.67 | ALDH1A1 (0.43) | MEN1ALDH1A1KMT2ASMN1; SMN2EPHX2 | |
| SCHEMBL23581880 | 0.66 | HSD17B10 (0.53) | MEN1ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113666930-A | Bridged pyrimidone compounds, preparation method, composition and application thereof | 上海纽思克生物科技有限公司 | 2021-11-19 | — | — | CN | disclosed |