Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.32 |
| ▸ | CDK2 | P24941 | 3/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21996615 | 0.81 | ESR1 (0.43) | ALDH1A1SMN1; SMN2PDE2ANPC1CDK1 | |
| SCHEMBL28644583 | 0.77 | AHR (0.49) | ALDH1A1HPGDKDM4ESMN1; SMN2GAA | |
| SCHEMBL21996594 | 0.74 | KDM4E (0.36) | ALDH1A1KDM4ECDK2POLBKDR | |
| SCHEMBL28647328 | 0.65 | IDH1 (0.38) | PDE2A | |
| SCHEMBL655771 | 0.63 | KMT2A (0.43) | ALDH1A1PDE2AL3MBTL1EGFR | |
| SCHEMBL6821654 | 0.63 | CTSL (0.59) | CDK2CTSLCDK1 | |
| SCHEMBL6364072 | 0.62 | PTK6 (0.34) | PIK3CDCDK2CCNA2CCNA1KDR | |
| SCHEMBL2317916 | 0.59 | CYP2D6 (0.47) | ALDH1A1SMN1; SMN2PDE2ACDK1 | |
| SCHEMBL10095261 | 0.59 | XDH (0.43) | ALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL20240186 | 0.59 | PDE2A (0.78) | PDE2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454076-A | Aromatic compounds for activating hematopoietic stem and progenitor cells | 细胞结构公司 | 2021-09-28 | — | — | CN | disclosed |