SCHEMBL28650337

SCHEMBL28650337

OCCc1cnn(Cc2cccc(C(F)(F)F)c2)c1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SCD5 Q86SK9 1/20 0.46
ADORA2B P29275 10/20 0.45
ADORA2A P29274 7/20 0.45
ADORA1 P30542 6/20 0.45
ADORA3 P0DMS8 6/20 0.45
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
GAA P10253 1/20 0.45
ALK Q9UM73 1/20 0.45
GPR52 Q9Y2T5 1/20 0.44
TAAR1 Q96RJ0 1/20 0.43
KDM4C Q9H3R0 1/20 0.42
HDAC1 Q13547 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2822182 0.89 ALK (0.48) SCD5ADORA2BADORA2AADORA1ADORA3
Hydrochloric Acid SCHEMBL21492794 0.83 MAOB (0.49) SCD5ADORA2BADORA2AADORA1ADORA3
Hydrochloric Acid SCHEMBL30744520 0.83 MAOB (0.49) SCD5ADORA2BADORA2AADORA1ADORA3
SCHEMBL24214370 0.80 ALDH1A1 (0.55) SCD5ADORA2BADORA2AADORA1ADORA3
SCHEMBL30376503 0.80 ALDH1A1 (0.55) SCD5ADORA2BADORA2AADORA1ADORA3
SCHEMBL3609013 0.80 MEN1 (0.59) SCD5ADORA2BADORA2AADORA1ADORA3
SCHEMBL243561 0.78 POLB (0.56) SCD5ADORA2BADORA2AADORA1ADORA3
SCHEMBL156739 0.78 TAAR1 (0.67) KDM4EALDH1A1GAATAAR1HDAC1
SCHEMBL30525290 0.78 TAAR1 (0.67) KDM4EALDH1A1GAATAAR1HDAC1
SCHEMBL12003036 0.77 MAOB (0.51) SCD5ADORA2BADORA2AADORA1ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113509467-A Compound for treating pulmonary hypertension and application thereof 华东理工大学 2021-10-19 CN disclosed