Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.48 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 11/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28650337 | 0.89 | SCD5 (0.46) | ALKSCD5ADORA2BADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL30744520 | 0.85 | MAOB (0.49) | ALKSCD5ADORA2BADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL21492794 | 0.85 | MAOB (0.49) | ALKSCD5ADORA2BADORA2AADORA1 | |
| SCHEMBL24214370 | 0.82 | ALDH1A1 (0.55) | ALKSCD5ADORA2BADORA2AADORA1 | |
| SCHEMBL3609013 | 0.82 | MEN1 (0.59) | ALKSCD5ADORA2BADORA2AADORA1 | |
| SCHEMBL30376503 | 0.82 | ALDH1A1 (0.55) | ALKSCD5ADORA2BADORA2AADORA1 | |
| SCHEMBL243561 | 0.80 | POLB (0.56) | SCD5ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL12003036 | 0.79 | MAOB (0.51) | SCD5ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL23045648 | 0.78 | SCD5 (0.53) | ALKSCD5ADORA2BADORA2AADORA1 | |
| SCHEMBL4766057 | 0.78 | ADORA2B (0.48) | ALKSCD5ADORA2BADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | MPM ASSET MANAGEMENT INVESTORS 2002 BVIII LLC | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | PPARA, PPARD, PPARG | ALK 3428/4885SCD5 420/4885ADORA2B 1077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.