Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1091118 | 0.73 | CA1 (0.41) | MAPTGAAKDM4EL3MBTL1NPC1 | |
| SCHEMBL1014275 | 0.70 | ALDH1A1 (0.50) | MAPTGAAKDM4ETHRBL3MBTL1 | |
| SCHEMBL1710455 | 0.70 | ALDH1A1 (0.50) | MAPTGAAKDM4ETHRBL3MBTL1 | |
| SCHEMBL2497019 | 0.63 | MAPT (0.48) | MAPTGAAKDM4ETHRBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11056785 | 0.62 | ADRA1A (0.37) | MAPTGAAKDM4ETHRBL3MBTL1 | |
| SCHEMBL10353931 | 0.62 | CYP19A1 (0.44) | MAPTGAAKDM4ETHRBL3MBTL1 | |
| SCHEMBL31484407 | 0.62 | CYP19A1 (0.44) | MAPTGAAKDM4ETHRBL3MBTL1 | |
| SCHEMBL21615521 | 0.62 | ALDH1A1 (0.48) | MAPTGAAKDM4ETHRBL3MBTL1 | |
| SCHEMBL19729185 | 0.61 | MAPT (0.57) | MAPTGAAKDM4ETHRBL3MBTL1 | |
| SCHEMBL358973 | 0.61 | ALDH1A1 (0.59) | MAPTGAAKDM4ETHRBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608435-B | Quinoline substituted indole compound, preparation method and application thereof | 中国药科大学 | 2021-10-29 | — | — | CN | disclosed |