Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | F2R | P25116 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28295475 | 0.87 | HPGD (0.55) | POLBHPGDCYP2C9CNR2CNR1 | |
| SCHEMBL28295487 | 0.86 | PLK1 (0.47) | POLBHPGDCYP2C9CNR2CNR1 | |
| SCHEMBL993102 | 0.81 | HPGD (0.65) | POLBHPGDCYP2C9CNR2KDM6B | |
| SCHEMBL28293667 | 0.80 | PLK1 (0.52) | POLBHPGDCYP2C9CNR2CNR1 | |
| SCHEMBL28655003 | 0.79 | KDM4E (0.53) | POLBHPGDCYP2C9CNR2CNR1 | |
| SCHEMBL9279131 | 0.77 | KMT2A (0.56) | HPGDCYP2C9CNR2CNR1KDM6B | |
| SCHEMBL466141 | 0.77 | PLK1 (0.63) | POLBHPGDCYP2C9CNR2CNR1 | |
| SCHEMBL11483067 | 0.76 | PLK1 (0.66) | HPGDCYP2C9CNR2CNR1KDM6B | |
| SCHEMBL5694119 | 0.76 | PLK1 (0.66) | HPGDCYP2C9CNR2CNR1KDM6B | |
| SCHEMBL11437269 | 0.76 | PLK1 (0.66) | HPGDCYP2C9CNR2CNR1KDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651179-B | 2- (2-aminobenzoyl) benzoic acid derivatives and process for preparing the same | 厦门华厦学院 | 2021-12-03 | — | — | CN | disclosed |