Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 9/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | KDM6B | O15054 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.45 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293669 | 0.92 | PLK1 (0.54) | PLK1KDM6BKDM4CPLK3CISD1 | |
| SCHEMBL28295487 | 0.91 | PLK1 (0.47) | PLK1POLBALDH1A1KDM4EGAA | |
| SCHEMBL9824061 | 0.88 | PLK1 (0.64) | PLK1KDM6BKDM4CPLK3CISD1 | |
| SCHEMBL28295475 | 0.86 | HPGD (0.55) | PLK1POLBALDH1A1KDM4EGAA | |
| SCHEMBL28655003 | 0.86 | KDM4E (0.53) | POLBALDH1A1KDM4EGAACNR1 | |
| SCHEMBL28110422 | 0.84 | PLK1 (0.67) | PLK1KDM6BKDM4CPLK3CISD1 | |
| SCHEMBL28650424 | 0.80 | APEX1 (0.50) | PLK1POLBALDH1A1KDM4EGAA | |
| SCHEMBL28669036 | 0.79 | KDM4C (0.78) | KDM4EKDM6BKDM4CMAPK8 | |
| SCHEMBL993102 | 0.77 | HPGD (0.65) | PLK1POLBALDH1A1KDM4ECNR2 | |
| SCHEMBL28109945 | 0.75 | PLK1 (0.67) | PLK1PLK3CISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651179-B | 2- (2-aminobenzoyl) benzoic acid derivatives and process for preparing the same | 厦门华厦学院 | 2021-12-03 | — | — | CN | disclosed |
| CN-109651179-A | 2- (2- amino benzoyl) benzoic acid derivative and preparation method thereof | 厦门华厦学院 | 2019-04-19 | — | — | CN | disclosed |