Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CISD1 | Q9NZ45 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293667 | 0.86 | PLK1 (0.52) | KDM4EALDH1A1CISD1POLBGAA | |
| SCHEMBL28295475 | 0.85 | HPGD (0.55) | KDM4EALDH1A1POLBGAACNR1 | |
| SCHEMBL28295487 | 0.80 | PLK1 (0.47) | KDM4EALDH1A1POLBGAACNR1 | |
| SCHEMBL15635741 | 0.80 | KDM4E (0.63) | KDM4EALDH1A1CISD1MEN1KMT2A | |
| SCHEMBL28650424 | 0.79 | APEX1 (0.50) | KDM4EALDH1A1POLBGAACNR1 | |
| SCHEMBL28293669 | 0.78 | PLK1 (0.54) | CISD1KDM6BKDM4C | |
| SCHEMBL28669036 | 0.78 | KDM4C (0.78) | KDM4EKDM6BKDM4C | |
| SCHEMBL993102 | 0.76 | HPGD (0.65) | KDM4EALDH1A1POLBCNR2KDM6B | |
| SCHEMBL21143482 | 0.75 | CISD1 (0.49) | KDM4EALDH1A1CISD1POLB | |
| SCHEMBL16696073 | 0.74 | KDM4E (0.52) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651179-B | 2- (2-aminobenzoyl) benzoic acid derivatives and process for preparing the same | 厦门华厦学院 | 2021-12-03 | — | — | CN | disclosed |