SCHEMBL28650574

SCHEMBL28650574

Clc1ccc(CCNCCc2ccc(Cl)cc2Cl)c(Cl)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.55
CNR1 P21554 1/20 0.54
IDO1 P14902 3/20 0.54
GPR84 Q9NQS5 1/20 0.53
MAPK1 P28482 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
HTT P42858 1/20 0.51
ALDH1A1 P00352 1/20 0.51
HPGD P15428 1/20 0.51
PLA2G1B P04054 1/20 0.49
ATG4B Q9Y4P1 1/20 0.49
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
PLAAT3 P53816 1/20 0.47
PLAAT5 Q96KN8 1/20 0.47
PLAAT2 Q9NWW9 1/20 0.47
PLAAT4 Q9UL19 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28654800 0.98 HTT (0.54) TAAR1CNR1IDO1GPR84MAPK1
SCHEMBL13995332 0.86 MEN1 (0.53) TAAR1CNR1IDO1GPR84MAPK1
SCHEMBL11621292 0.84 IDO1 (0.65) CNR1IDO1GPR84MAPK1CYP1A2
SCHEMBL6894441 0.83 CNR1 (0.51) TAAR1CNR1IDO1GPR84MAPK1
SCHEMBL680436 0.83 TAAR1 (0.60) TAAR1CNR1IDO1GPR84MAPK1
SCHEMBL2856783 0.83 CNR1 (0.51) TAAR1CNR1IDO1GPR84MAPK1
SCHEMBL5405695 0.82 TAAR1 (0.59) TAAR1CNR1GPR84ALDH1A1HPGD
Hydrochloric Acid SCHEMBL20529751 0.82 MAPK1 (0.52) TAAR1CNR1IDO1GPR84MAPK1
SCHEMBL5099392 0.81 SIGMAR1 (0.47) TAAR1CNR1IDO1GPR84MAPK1
SCHEMBL31439249 0.81 PLA2G1B (0.55) TAAR1CNR1GPR84ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113735715-A Bis (2, 4-dichlorophenethyl) amine hydrochloride and preparation method thereof 山东金城柯瑞化学有限公司 2021-12-03 CN disclosed