Sugi Predict

Sugi Predict / Compounds / SCHEMBL2865112

SCHEMBL2865112

SCHEMBL2865112

Nc1c(Cl)cc(S(=O)(=O)O)cc1Cl

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 6/20 0.64
▸ CA2 P00918 6/20 0.64
▸ CA9 Q16790 6/20 0.64
▸ TDP1 Q9NUW8 2/20 0.52
▸ L3MBTL1 Q9Y468 2/20 0.52
▸ POLB P06746 1/20 0.52
▸ APEX1 P27695 1/20 0.52
▸ ALDH1A1 P00352 7/20 0.46
▸ CYP3A4 P08684 2/20 0.46
▸ TSHR P16473 3/20 0.44
▸ NT5E P21589 2/20 0.44
▸ HSD17B10 Q99714 4/20 0.43
▸ THRB P10828 1/20 0.42
▸ HPGD P15428 1/20 0.42
▸ ALOX15 P16050 1/20 0.42
▸ CASP1 P29466 1/20 0.42
▸ RECQL P46063 1/20 0.42
▸ CA12 O43570 1/20 0.42
▸ CA4 P22748 1/20 0.42
▸ CA6 P23280 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7948500 0.98 CA1 (0.61) CA1CA2CA9TDP1L3MBTL1
SCHEMBL7516755 0.89 TDP1 (0.57) CA1CA2CA9TDP1L3MBTL1
SCHEMBL11815347 0.86 CA1 (0.72) CA1CA2CA9TDP1L3MBTL1
SCHEMBL7822495 0.86 CA2 (0.48) CA1CA2CA9TDP1L3MBTL1
SCHEMBL28813232 0.81 CA1 (0.44) CA1CA2CA9TDP1L3MBTL1
SCHEMBL29918476 0.80 NT5E (0.47) CA1CA2CA9TDP1L3MBTL1
SCHEMBL6935562 0.80 CASP6 (0.53) CA1CA2CA9TDP1L3MBTL1
SCHEMBL5981987 0.80 CA1 (0.70) CA1CA2CA9TDP1L3MBTL1
SCHEMBL3139602 0.80 CA1 (0.45) CA1CA2CA9TDP1ALDH1A1
SCHEMBL9768977 0.79 CA2 (0.42) CA1CA2CA9TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084680-A Preparation method of 2, 6-dichloroaniline 黑龙江立科新材料有限公司 2024-05-28 — — CN claimed
CN-118084680-A Preparation method of 2, 6-dichloroaniline 黑龙江立科新材料有限公司 2024-05-28 — — CN disclosed
CN-118084680-A Preparation method of 2, 6-dichloroaniline 黑龙江立科新材料有限公司 2024-05-28 — — CN disclosed
CN-112358405-B Method for preparing dichloroaniline through chlorination 兰州深蓝化学有限公司 2023-03-24 — — CN disclosed
CN-112358405-A Method for preparing dichloroaniline through chlorination 兰州深蓝化学有限公司 2021-02-12 — — CN disclosed
US-20140084578-A1 AZO COMPOUND, AQUEOUS SOLUTION, INK COMPOSITION, INK FOR INKJET RECORDING, INKJET RECORDING METHOD, INK CARTRIDGE FOR INKJET RECORDING, AND INKJET RECORDED MATERIAL FUJIFILM CORPORATION (JP) 2014-03-27 — — US disclosed
CN-103664915-A Azo compound, aqueous solution, ink composition, ink for inkjet recording, inkjet recording method, ink cartridge for inkjet recording, and inkjet recorded material FUJIFILM CORP 2014-03-26 — — CN disclosed
US-8349865-B2 Inhibitors of janus kinases MERCK SHARP & DOHME CORP. (US) 2013-01-08 — — US disclosed
EP-2200612-B1 INHIBITORS OF JANUS KINASES SCHERING CORP (US) 2012-08-08 — — EP disclosed
US-20100197634-A1 INHIBITORS OF JANUS KINASES MERCK SHARP & DOHME LLC 2010-08-05 — — US disclosed
EP-0119441-B1 REACTIVE DYES WITH SUBSTITUTED 4-FLUOROPYRIDAZ-6-ONE GROUPS BASF Aktiengesellschaft (DE) 1987-02-25 — — EP disclosed
EP-0045488-B1 WATER-SOLUBLE FIBRE-REACTIVE COMPOUNDS AND THEIR USE IN FINISHING TEXTILES, AS WELL AS THE BETA-CHLOROETHYL-SULFONYL-METHYL-BENZOIC-ACID HALOGENIDES, AND THEIR USE AS A FIBRE-REACTIVE ANCHOR HOECHST AKTIENGESELLSCHAFT (DE) 1985-06-19 — — EP disclosed
EP-0133270-A1 Reactive dyes BASF Aktiengesellschaft (DE) 1985-02-20 — — EP disclosed
EP-0119441-A2 Reactive dyes with substituted 4-fluoropyridaz-6-one groups BASF Aktiengesellschaft (DE) 1984-09-26 — — EP disclosed
US-4473498-A Water-soluble, fiber-reactive organic dyestuffs containing a β-chloro-ethylsulfonyl-methyl-benzoic acid amide group HOECHST AKTIENGESELLSCHAFT (DE) 1984-09-25 — — US disclosed
EP-0012969-B1 WATER-SOLUBLE FIBRE-REACTIVE COMPOUNDS AND THEIR USE IN FIBRE FINISHING,ESPECIALLY AS DYESTUFFS,AND DIHALOGENO-PYRIDAZONYL-CARBOXYLIC AND SULFONIC ACID HALIDES AND THEIR USE AS FIBRE-REACTIVE ANCHORS,AS WELL AS PROCESS FOR THE PREPARATION OF THESE COMPOUND HOECHST AKTIENGESELLSCHAFT (DE) 1983-06-08 — — EP disclosed
EP-0045488-A2 Water-soluble fibre-reactive compounds and their use in finishing textiles, as well as the beta-chloroethyl-sulfonyl-methyl-benzoic-acid halogenides, and their use as a fibre-reactive anchor HOECHST AKTIENGESELLSCHAFT (DE) 1982-02-10 — — EP disclosed
EP-0012969-A2 Water-soluble fibre-reactive compounds and their use in fibre finishing,especially as dyestuffs,and dihalogeno-pyridazonyl-carboxylic and sulfonic acid halides and their use as fibre-reactive anchors,as well as process for the preparation of these compound HOECHST AKTIENGESELLSCHAFT (DE) 1980-07-09 — — EP disclosed
US-4055557-A MONOAZO DYES BAYER AKTIENGESELLSCHAFT (DT) 1977-10-25 — — US disclosed
US-4014647-A DISPERSE DYES CONTAINING SULFONAMIDE GROUPS BAYER AKTIENGESELLSCHAFT (DT) 1977-03-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100197634-A1 INHIBITORS OF JANUS KINASES JAK2, JAK3, JAK1 CA1 4649/4885CA2 3829/4885CA9 4228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.