Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GRN | P28799 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28648734 | 0.88 | THRB (0.48) | POLBALDH1A1THRBHTTKMT2A | |
| SCHEMBL28783041 | 0.85 | KLKB1 (0.49) | KLKB1GAAPOLBALDH1A1GRN | |
| SCHEMBL28782960 | 0.82 | FFAR4 (0.39) | GAAPOLBALDH1A1GRNSORT1 | |
| SCHEMBL28783042 | 0.79 | ALDH1A1 (0.42) | KLKB1GAAPOLBALDH1A1GRN | |
| SCHEMBL6413900 | 0.79 | KMT2A (0.54) | KLKB1GAAALDH1A1GRNSORT1 | |
| SCHEMBL28782978 | 0.78 | SCN9A (0.48) | GAAPOLBALDH1A1THRBHTT | |
| SCHEMBL27889993 | 0.77 | HTT (0.51) | KLKB1GAAPOLBALDH1A1GRN | |
| SCHEMBL2927650 | 0.76 | ALDH1A1 (0.74) | KLKB1GAAPOLBALDH1A1THRB | |
| SCHEMBL28668926 | 0.76 | ALDH1A1 (0.46) | KLKB1GAAPOLBALDH1A1GRN | |
| SCHEMBL2314764 | 0.75 | GRN (0.74) | KLKB1GAAALDH1A1GRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621145-A | Diphenylamide derivatives of fluorophenyl and trifluoroethoxy pyrazole, and preparation method and application thereof | 南开大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-112939866-A | Fluorine-substituted phenyl pyrazole amide derivative and preparation method and application thereof | 南开大学 | 2021-06-11 | — | — | CN | disclosed |