SCHEMBL28652108

SCHEMBL28652108

CC(C)C[Al](CC(C)C)Oc1cccc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 8/20 0.46
NR2E1 Q9Y466 6/20 0.45
HTR1D P28221 1/20 0.42
CYP2D6 P10635 4/20 0.42
CYP1A2 P05177 4/20 0.42
SLC6A4 P31645 4/20 0.42
ADRB2 P07550 4/20 0.42
ADRB1 P08588 4/20 0.42
SIGMAR1 Q99720 4/20 0.42
HTR2B P41595 3/20 0.42
ALDH1A1 P00352 3/20 0.42
ADRB3 P13945 3/20 0.42
HTR2A P28223 3/20 0.42
HTR2C P28335 3/20 0.42
HTR6 P50406 3/20 0.42
SCN1A P35498 2/20 0.42
SLC10A1 Q14973 2/20 0.42
SCN2A Q99250 2/20 0.42
SCN3A Q9NY46 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28665971 0.77 CYP1A2 (0.40) CYP2D6CYP1A2SLC6A4ADRB2ADRB1
SCHEMBL5031818 0.73 NR2E1 (0.64) HTR1BNR2E1HTR1DCYP2D6CYP1A2
SCHEMBL29829725 0.73 NR2E1 (0.64) HTR1BNR2E1HTR1DCYP2D6CYP1A2
SCHEMBL8344968 0.70 HTR1B (0.64) HTR1BNR2E1HTR1DSLC6A4ALDH1A1
SCHEMBL28648150 0.70 CYP1A2 (0.47) CYP1A2HTR2BHTR2AHTR2CSMN1; SMN2
SCHEMBL4982131 0.70 CYP1A2 (0.56) HTR1BNR2E1HTR1DCYP2D6CYP1A2
SCHEMBL6831487 0.70 HTR1B (0.50) HTR1BNR2E1HTR1DCYP2D6CYP1A2
SCHEMBL27265895 0.69 HTR1B (0.62) HTR1BNR2E1HTR1DSLC6A4ALDH1A1
SCHEMBL17286559 0.69 HTR1B (0.65) HTR1BNR2E1HTR1DSLC6A4HRH1
SCHEMBL9477167 0.68 MCHR1 (0.54) HTR1BNR2E1HTR1DCYP2D6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113527561-B Molybdenum-based catalyst for catalyzing butadiene to polymerize with high 1, 2-selectivity and application method thereof 青岛科技大学 2022-07-08 CN disclosed
CN-113527561-A Molybdenum-based catalyst for catalyzing butadiene to polymerize with high 1, 2-selectivity and application method thereof 青岛科技大学 2021-10-22 CN disclosed