Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | IAPP | P10997 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14303656 | 1.00 | CYP1A1 (0.55) | CYP1A1CYP1B1MAPTMEN1KMT2A | |
| SCHEMBL31356822 | 1.00 | CYP1A1 (0.55) | CYP1A1CYP1B1MAPTMEN1KMT2A | |
| SCHEMBL2865213 | 1.00 | CYP1A1 (0.55) | CYP1A1CYP1B1MAPTMEN1KMT2A | |
| SCHEMBL584566 | 0.85 | CYP1A1 (0.55) | CYP1A1CYP1B1MAPTMEN1KMT2A | |
| SCHEMBL30278658 | 0.85 | CYP1A1 (0.55) | CYP1A1CYP1B1MAPTMEN1KMT2A | |
| SCHEMBL584565 | 0.85 | CYP1A1 (0.55) | CYP1A1CYP1B1MAPTMEN1KMT2A | |
| SCHEMBL15826781 | 0.85 | MAPT (0.54) | CYP1A1CYP1B1MAPTMEN1KMT2A | |
| SCHEMBL8140673 | 0.83 | CYP1A1 (0.54) | CYP1A1CYP1B1MAPTMEN1KMT2A | |
| SCHEMBL18517696 | 0.83 | MAPT (0.50) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL2130414 | 0.83 | CYP1A1 (0.54) | CYP1A1CYP1B1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873281-B2 | Conjugates of cell binding molecules with cytotoxic agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2024-01-16 | — | — | US | disclosed |
| US-11834406-B2 | Conjugates of cell binding molecules with cytotoxic agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-12-05 | — | — | US | disclosed |
| US-11767294-B2 | Conjugates of cell binding molecules with cytotoxic agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-09-26 | — | — | US | disclosed |
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-08-03 | — | — | US | disclosed |
| US-20230165931-A1 | A CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-06-01 | — | — | US | disclosed |
| US-20230165930-A1 | CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-06-01 | — | — | US | disclosed |
| US-20230149502-A1 | CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-05-18 | — | — | US | disclosed |
| US-9988408-B2 | Cytotoxic agents for conjugation to a cell binding molecule | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2018-06-05 | — | — | US | disclosed |
| US-20180021448-A9 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2018-01-25 | — | — | US | disclosed |
| US-20170296663-A1 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2017-10-19 | — | — | US | disclosed |
| US-9340634-B2 | Polymer for use in liquid crystal alignment layer | DIC CORPORATION (JP) | 2016-05-17 | — | — | US | disclosed |
| US-9340634-B2 | Polymer for use in liquid crystal alignment layer | DIC CORPORATION (JP) | 2016-05-17 | — | — | US | disclosed |
| US-20130116396-A1 | POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER | DIC CORPORATION (JP) | 2013-05-09 | — | — | US | disclosed |
| US-20130116396-A1 | POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER | DIC CORPORATION (JP) | 2013-05-09 | — | — | US | disclosed |
| US-7772249-B2 | Imidazo[1,2-b]pyridazine compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| US-20090181985-A1 | IMIDAZO[1,2-b]PYRIDAZINE COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
| US-20060211696-A1 | IMIDAZO[1,2-b]PYRIDAZINE COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2006-09-21 | — | — | US | disclosed |
| US-7078405-B2 | Imidazo[1,2-b]pyridazine compound | EISAI CO., LTD. (JP) | 2006-07-18 | — | — | US | disclosed |
| US-20040082781-A1 | Bicyclic nitrogenous fused-ring compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1364952-A1 | BICYCLIC NITROGENOUS FUSED-RING COMPOUND | Eisai Co., Ltd. (JP) | 2003-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165930-A1 | CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS | TEKT1, CD2BP2, TEK | CYP1A1 4844/4885CYP1B1 4690/4885MAPT 2605/4885 |
| US-20060211696-A1 | IMIDAZO[1,2-b]PYRIDAZINE COMPOUND | CRHR1, CRHR2, CRH | CYP1A1 1287/4885CYP1B1 1440/4885MAPT 4874/4885 |
| US-20230165931-A1 | A CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS | TEKT1, CD2BP2, CD4 | CYP1A1 4827/4885CYP1B1 4645/4885MAPT 2616/4885 |
| US-11873281-B2 | Conjugates of cell binding molecules with cytotoxic agents | CD4, CD2, CD47 | CYP1A1 3956/4885CYP1B1 4430/4885MAPT 4147/4885 |
| US-20090181985-A1 | IMIDAZO[1,2-b]PYRIDAZINE COMPOUND | CRHR1, CRHR2, CRH | CYP1A1 1287/4885CYP1B1 1440/4885MAPT 4874/4885 |
| US-11767294-B2 | Conjugates of cell binding molecules with cytotoxic agents | CD4, CD2, CD47 | CYP1A1 3880/4885CYP1B1 4489/4885MAPT 4393/4885 |
| US-20180021448-A9 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | CD4, CD2, CD47 | CYP1A1 3880/4885CYP1B1 4489/4885MAPT 4393/4885 |
| US-20170296663-A1 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | CD4, CD2, CD47 | CYP1A1 3880/4885CYP1B1 4489/4885MAPT 4393/4885 |
| US-20040082781-A1 | Bicyclic nitrogenous fused-ring compound | CRHR1, CRH, CRHR2 | CYP1A1 1470/4885CYP1B1 1557/4885MAPT 4834/4885 |
| US-20230149502-A1 | CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS | TEKT1, CD2BP2, TEK | CYP1A1 4844/4885CYP1B1 4690/4885MAPT 2605/4885 |
| US-11834406-B2 | Conjugates of cell binding molecules with cytotoxic agents | CD4, CD2, CD47 | CYP1A1 4034/4885CYP1B1 4618/4885MAPT 4352/4885 |
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | CD4, DCLRE1A, TOP1 | CYP1A1 3360/4885CYP1B1 3083/4885MAPT 3691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.