SCHEMBL661077

SCHEMBL661077

O=C=Nc1cc2ccccc2cc1N=C=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.48
TRPA1 O75762 1/20 0.42
ALDH1A1 P00352 3/20 0.39
HPGD P15428 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.36
RAD52 P43351 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
MAPK1 P28482 2/20 0.36
HSD17B10 Q99714 2/20 0.36
TSHR P16473 2/20 0.36
TP53 P04637 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
HIF1A Q16665 1/20 0.36
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
GRIN2D O15399 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29589760 1.00 CYP3A4 (0.48) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL48303 0.95 CYP3A4 (0.45) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL1169526 0.84 CYP3A4 (0.43) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL3714186 0.79 CYP3A4 (0.48) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL28688754 0.79 MEN1 (0.44) CYP3A4ALDH1A1HPGDTDP1MAPT
SCHEMBL15431 0.78 CYP3A4 (0.64) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL29395383 0.78 CYP3A4 (0.64) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL11334193 0.78 CYP3A4 (0.48) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL112471 0.78 POLB (0.41) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL9701447 0.76 ALDH1A1 (0.43) CYP3A4TRPA1ALDH1A1HPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9371504-B2 Use of acrylate copolymers as soil antiredeposition agents and soil release agents in laundry processes BASF SE (DE) 2016-06-21 US claimed
CN-104145012-A USE OF ACRYLATE COPOLYMERS AS SOIL ANTIREDEPOSITION AGENTS AND SOIL RELEASE AGENTS IN LAUNDRY PROCESSES BASF SE 2014-11-12 CN claimed
US-20140287974-A1 USE OF ACRYLATE COPOLYMERS AS SOIL ANTIREDEPOSITION AGENTS AND SOIL RELEASE AGENTS IN LAUNDRY PROCESSES BASF SE (DE) 2014-09-25 US claimed
EP-2771446-A1 USE OF ACRYLATE COPOLYMERS AS SOIL ANTIREDEPOSITION AGENTS AND SOIL RELEASE AGENTS IN LAUNDRY PROCESSES BASF SE (DE) 2014-09-03 EP claimed
EP-2488565-B1 AQUEOUS STOVING BINDER ALLNEX AUSTRIA GMBH (AT) 2014-08-20 EP claimed
WO-2013060706-A1 USE OF ACRYLATE COPOLYMERS AS SOIL ANTIREDEPOSITION AGENTS AND SOIL RELEASE AGENTS IN LAUNDRY PROCESSES BASF SE (DE) 2013-05-02 WO claimed
EP-2344112-A1 SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A RANDOM TERPOLYMER BASF SE (DE) 2011-07-20 EP claimed
EP-2340088-A2 COLOR COSMETIC COMPRISING A RANDOM TERPOLYMER BASF SE (DE) 2011-07-06 EP claimed
US-20100129303-A1 SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A RANDOM TERPOLYMER BASF SE (DE) 2010-05-27 US claimed
US-20100104610-A1 Color cosmetics comprising a random terpolymer BASF SE (DE) 2010-04-29 US claimed
EP-0507727-B1 Glass coating with improved adhesion and weather resistance CIBA GEIGY AG (CH) 1997-01-22 EP claimed
EP-0493320-B1 Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof CIBA GEIGY AG (CH) 1996-07-31 EP claimed
EP-0694532-A1 Perfluoroalkyl sulfide, sulfone, polysulfone and polysulfide diols CIBA-GEIGY AG (CH) 1996-01-31 EP claimed
EP-0690039-A2 Poly-perfluoroalkyl-substituted alcohols and acids, and derivatives thereof CIBA-GEIGY AG (CH) 1996-01-03 EP claimed
EP-0362145-B1 Crosslinked siloxane-urethane polymer contact lens CIBA GEIGY AG (CH) 1996-01-03 EP claimed
EP-0406161-B1 Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof CIBA GEIGY AG (CH) 1995-02-22 EP claimed
EP-0367720-B1 Novel polysiloxane-polyurethanes and contact lenses thereof CIBA GEIGY AG (CH) 1994-07-20 EP claimed
EP-0455585-B1 Unsaturated urea polysiloxanes CIBA GEIGY AG (CH) 1994-03-23 EP claimed
US-5200493-A Polyurethanes and polythiourethanes; protective coatings; oil repellents; waterproofing; antisoilants CIBA-GEIGY CORPORATION (US) 1993-04-06 US claimed
EP-0362145-A2 Crosslinked siloxane-urethane polymer contact lens CIBA-GEIGY AG (CH) 1990-04-04 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100129303-A1 SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A RANDOM TERPOLYMER MITF, TYR, MSH6 CYP3A4 920/4885TRPA1 166/4885ALDH1A1 2271/4885
US-20100104610-A1 Color cosmetics comprising a random terpolymer CUTA, TYR, MSH6 CYP3A4 2793/4885TRPA1 448/4885ALDH1A1 1313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.