Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 18/20 | 0.63 |
| ▸ | LCK | P06239 | 17/20 | 0.63 |
| ▸ | EGFR | P00533 | 7/20 | 0.59 |
| ▸ | BTK | Q06187 | 15/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21855199 | 1.00 | JAK3 (0.63) | JAK3LCKEGFRBTK | |
| SCHEMBL31039883 | 1.00 | JAK3 (0.63) | JAK3LCKEGFRBTK | |
| SCHEMBL28639774 | 0.88 | JAK3 (0.68) | JAK3LCKEGFRBTK | |
| SCHEMBL31039879 | 0.88 | JAK3 (0.68) | JAK3LCKEGFRBTK | |
| SCHEMBL21855193 | 0.88 | JAK3 (0.68) | JAK3LCKEGFRBTK | |
| SCHEMBL30011519 | 0.87 | JAK3 (0.70) | JAK3LCKEGFRBTK | |
| SCHEMBL28653137 | 0.87 | JAK3 (0.70) | JAK3LCKEGFRBTK | |
| SCHEMBL28653136 | 0.87 | JAK3 (0.70) | JAK3LCKEGFRBTK | |
| SCHEMBL21946758 | 0.86 | JAK3 (0.64) | JAK3LCKEGFRBTK | |
| SCHEMBL21855166 | 0.85 | JAK3 (0.63) | JAK3LCKEGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113412259-A | Bifunctional compounds for the degradation of BTK via the ubiquitin proteasome pathway | 紐力克斯治疗公司 | 2021-09-17 | — | — | CN | disclosed |