Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL286402 | 0.95 | GABRA1 (0.67) | GABRA1ITGA5 | |
| SCHEMBL286518 | 0.95 | GABRA1 (0.67) | GABRA1ITGA5 | |
| SCHEMBL285756 | 0.86 | GABRA5 (0.70) | GABRA1ITGA5 | |
| SCHEMBL286587 | 0.84 | GABRA1 (0.56) | GABRA1ITGA5 | |
| SCHEMBL15663247 | 0.84 | GABRA1 (0.54) | GABRA1ITGA5 | |
| SCHEMBL286280 | 0.83 | GABRA1 (0.49) | GABRA1ITGA5 | |
| SCHEMBL1776675 | 0.82 | ITGA5 (0.81) | GABRA1ITGA5 | |
| SCHEMBL286586 | 0.82 | GABRA1 (0.62) | GABRA1 | |
| SCHEMBL285768 | 0.82 | GABRA5 (0.69) | GABRA1ITGA5 | |
| SCHEMBL285417 | 0.82 | GABRA5 (0.69) | GABRA1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427458-A1 | ISOXAZOLE-PYRIDAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2012-03-14 | — | — | EP | claimed |
| EP-2427458-A1 | ISOXAZOLE-PYRIDAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2012-03-14 | — | — | EP | disclosed |