Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 6/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | GFER | P55789 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | SNCA | P37840 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12584908 | 0.86 | ABCB1 (0.76) | ABCB1LMNAMAPTMEN1KMT2A | |
| SCHEMBL9190681 | 0.86 | ABCB1 (0.76) | ABCB1LMNAMAPTMEN1KMT2A | |
| SCHEMBL21409745 | 0.86 | MEN1 (0.59) | ABCB1LMNAMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3718293 | 0.85 | ALDH1A1 (0.69) | ABCB1LMNAMAPTMEN1KMT2A | |
| SCHEMBL1458219 | 0.85 | ABCB1 (0.74) | ABCB1LMNAMAPTMEN1KMT2A | |
| SCHEMBL16656727 | 0.85 | ABCB1 (0.74) | ABCB1LMNAMAPTMEN1KMT2A | |
| SCHEMBL1458094 | 0.85 | MEN1 (0.74) | ABCB1LMNAMAPTMEN1KMT2A | |
| SCHEMBL707585 | 0.84 | MEN1 (0.89) | ABCB1LMNAMAPTMEN1KMT2A | |
| SCHEMBL5148402 | 0.84 | MEN1 (0.60) | ABCB1LMNAMAPTMEN1KMT2A | |
| SCHEMBL28707478 | 0.84 | AURKB (0.67) | ABCB1LMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549043-B | Flavonoid tankyrase 2 inhibitor and preparation method and application thereof | 上海应用技术大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-113461612-B | Quinolone tankyrase 2 inhibitor and preparation method and application thereof | 上海应用技术大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-113549043-A | Flavonoid tankyrase 2 inhibitor and preparation method and application thereof | 上海应用技术大学 | 2021-10-26 | — | — | CN | disclosed |
| CN-113461612-A | Quinolone tankyrase 2 inhibitor and preparation method and application thereof | 上海应用技术大学 | 2021-10-01 | — | — | CN | disclosed |