SCHEMBL28653252

SCHEMBL28653252

CCCCC(C)Cc1cccc2sc(SN)nc12

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 2/20 0.34
HSP90AB1 P08238 2/20 0.34
PTGS2 P35354 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28642759 0.88 HSP90AA1 (0.34) HSP90AA1HSP90AB1PTGS2MEN1KMT2A
SCHEMBL30305194 0.82 PTGS2 (0.41) HSP90AA1HSP90AB1PTGS2MEN1KMT2A
SCHEMBL583151 0.82 PTGS2 (0.41) HSP90AA1HSP90AB1PTGS2MEN1KMT2A
SCHEMBL2671226 0.81 PTGS2 (0.45) HSP90AA1HSP90AB1PTGS2MEN1KMT2A
SCHEMBL23174999 0.80 PTGS2 (0.47) HSP90AA1HSP90AB1PTGS2
SCHEMBL28375837 0.80 PTGS2 (0.47) HSP90AA1HSP90AB1PTGS2
SCHEMBL28701435 0.80 PTGS2 (0.47) HSP90AA1HSP90AB1PTGS2
SCHEMBL28299064 0.79 MEN1 (0.47) MEN1KMT2A
SCHEMBL20680362 0.71 ALDH1A1 (0.33) HSP90AA1HSP90AB1MEN1KMT2A
SCHEMBL9193542 0.70 ALDH1A1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107868286-B Rubber composition for coating steel cord and tire 住友橡胶工业株式会社 2021-11-09 CN disclosed