Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2711475 | 0.88 | ALDH1A1 (0.58) | ALDH1A1GAAL3MBTL1RAB9ANPC1 | |
| SCHEMBL15557817 | 0.79 | ALDH1A1 (0.49) | ALDH1A1GAAL3MBTL1HPGDRAB9A | |
| SCHEMBL11900465 | 0.79 | PDE10A (0.46) | ALDH1A1GAAL3MBTL1RAB9AMEN1 | |
| SCHEMBL29940575 | 0.79 | PDE10A (0.60) | ALDH1A1GAAL3MBTL1RAB9ANPC1 | |
| SCHEMBL6512953 | 0.79 | PDE10A (0.60) | ALDH1A1GAAL3MBTL1RAB9ANPC1 | |
| SCHEMBL28653396 | 0.78 | PDE10A (0.45) | ALDH1A1GAAL3MBTL1RAB9ANPC1 | |
| SCHEMBL3208138 | 0.78 | L3MBTL1 (0.58) | ALDH1A1GAAL3MBTL1HPGDRAB9A | |
| SCHEMBL11406237 | 0.78 | HPGD (0.68) | ALDH1A1GAAL3MBTL1HPGDRAB9A | |
| SCHEMBL1736405 | 0.77 | ALDH1A1 (0.57) | ALDH1A1GAAL3MBTL1HPGDRAB9A | |
| SCHEMBL13556883 | 0.76 | POLB (0.53) | ALDH1A1GAAL3MBTL1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112125840-B | Based on CO2Method for preparing diaryl ether compound by participated C-F bond activation | 河南师范大学 | 2021-10-15 | — | — | CN | disclosed |
| CN-112125840-A | Based on CO2Method for preparing diaryl ether compound by participated C-F bond activation | 河南师范大学 | 2020-12-25 | — | — | CN | disclosed |