Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31039876 | 1.00 | MAP2K4 (0.35) | MAP2K4GRM5SSTR4FAAHBRD4 | |
| SCHEMBL17916962 | 0.84 | GABRG2 (0.36) | MAP2K4GRM5SSTR4FAAHBRD4 | |
| SCHEMBL31092006 | 0.83 | MAP2K4 (0.40) | MAP2K4FAAHBRD4MAPTELANE | |
| SCHEMBL2361004 | 0.78 | POLB (0.41) | MAP2K4GRM5SSTR4FAAHBRD4 | |
| SCHEMBL29640143 | 0.78 | POLB (0.41) | MAP2K4GRM5SSTR4FAAHBRD4 | |
| SCHEMBL2674135 | 0.73 | MAP2K4 (0.44) | MAP2K4FAAHELANEBCHEP2RX3 | |
| SCHEMBL15541538 | 0.72 | MAP2K4 (0.43) | MAP2K4SSTR4BRD4ELANEGABRG2 | |
| SCHEMBL16606155 | 0.71 | L3MBTL1 (0.40) | GRM5SSTR4BRD4GPR119BCHE | |
| SCHEMBL24148158 | 0.71 | MAP2K4 (0.43) | MAP2K4BCHE | |
| SCHEMBL29913685 | 0.70 | SSTR4 (0.39) | GRM5SSTR4BRD4GPR119BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113412259-B | Difunctional compounds for degrading BTK via the ubiquitin proteasome pathway | 紐力克斯治疗公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-113412259-A | Bifunctional compounds for the degradation of BTK via the ubiquitin proteasome pathway | 紐力克斯治疗公司 | 2021-09-17 | — | — | CN | disclosed |