Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28653417 | 1.00 | ALDH1A1 (0.49) | ALDH1A1KMT2AKDM4EPKMPOLB | |
| SCHEMBL28647747 | 0.90 | ALDH1A1 (0.55) | ALDH1A1KMT2AKDM4EPKMPOLB | |
| SCHEMBL28647750 | 0.90 | ALDH1A1 (0.55) | ALDH1A1KMT2AKDM4EPKMPOLB | |
| SCHEMBL25200494 | 0.84 | ALDH1A1 (0.60) | ALDH1A1KMT2AKDM4EPKMPOLB | |
| SCHEMBL2916065 | 0.82 | ALDH1A1 (0.67) | ALDH1A1KMT2AKDM4EPKMPOLB | |
| SCHEMBL2909486 | 0.82 | ALDH1A1 (0.67) | ALDH1A1KMT2AKDM4EPKMPOLB | |
| SCHEMBL28657828 | 0.81 | MEN1 (0.45) | ALDH1A1KMT2AKDM4EMEN1VCP | |
| SCHEMBL28657829 | 0.81 | MEN1 (0.45) | ALDH1A1KMT2AKDM4EMEN1VCP | |
| SCHEMBL8652597 | 0.78 | VCP (0.69) | ALDH1A1KMT2AKDM4ECES2CES1 | |
| SCHEMBL28653420 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KMT2AKDM4EPKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113651755-B | 4-azafluorene compound and preparation method and application thereof | 山东师范大学 | 2022-07-29 | — | — | CN | claimed |
| CN-113651755-A | 4-azafluorene compound and preparation method and application thereof | 山东师范大学 | 2021-11-16 | — | — | CN | claimed |
| CN-113651755-B | 4-azafluorene compound and preparation method and application thereof | 山东师范大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-113651755-A | 4-azafluorene compound and preparation method and application thereof | 山东师范大学 | 2021-11-16 | — | — | CN | disclosed |