Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 6/20 | 0.44 |
| ▸ | MAOA | P21397 | 6/20 | 0.44 |
| ▸ | MAOB | P27338 | 6/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9067468 | 0.83 | TRPA1 (0.46) | TRPA1KDM1AMAOAMAOBPTGS2 | |
| SCHEMBL20437086 | 0.79 | TRPA1 (0.47) | OPRM1OPRL1TRPA1OPRK1OPRD1 | |
| SCHEMBL23259467 | 0.76 | MAOB (0.50) | OPRM1OPRL1KDM1AMAOAMAOB | |
| SCHEMBL23259077 | 0.76 | OPRM1 (0.47) | OPRM1OPRL1GRIN2BOPRK1OPRD1 | |
| SCHEMBL12975993 | 0.72 | OPRM1 (0.49) | OPRM1OPRL1GRIN2BOPRK1OPRD1 | |
| SCHEMBL16993536 | 0.72 | GRIN2B (0.47) | OPRM1OPRL1GRIN2BOPRK1OPRD1 | |
| SCHEMBL12093047 | 0.72 | OPRM1 (0.49) | OPRM1OPRL1GRIN2BOPRK1OPRD1 | |
| SCHEMBL21214372 | 0.72 | OPRM1 (0.54) | OPRM1OPRL1GRIN2BOPRK1OPRD1 | |
| SCHEMBL7254284 | 0.72 | TRPA1 (0.53) | TRPA1KDM1AMAOAMAOB | |
| SCHEMBL28922633 | 0.71 | TRPA1 (0.41) | TRPA1KDM1AMAOAMAOBPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894141-B | Method for synthesizing acyl indene alkane derivative | 贺州学院 | 2023-12-22 | — | — | CN | disclosed |
| CN-115894141-A | Synthesis method of acylindene derivatives | 贺州学院 | 2023-04-04 | — | — | CN | disclosed |
| CN-113651752-B | Synthesis method of 2-aroylquinoline derivative | 温州大学 | 2023-02-10 | — | — | CN | disclosed |
| CN-113636977-B | Synthesis method of 2-aryl benzazepine and derivatives thereof | 温州大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-113651752-A | Synthesis method of 2-aroylquinoline derivative | 温州大学 | 2021-11-16 | — | — | CN | disclosed |
| CN-113636977-A | Synthesis method of 2-aryl benzazepine and derivatives thereof | 温州大学 | 2021-11-12 | — | — | CN | disclosed |