Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28671557 | 0.90 | MEN1 (0.72) | MEN1KMT2ASMN1; SMN2LMNAGAA | |
| SCHEMBL28653579 | 0.90 | KMT2A (0.56) | MEN1KMT2ASMN1; SMN2LMNAGAA | |
| SCHEMBL28669019 | 0.89 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2LMNAGAA | |
| SCHEMBL28654555 | 0.88 | RAB9A (0.66) | MEN1KMT2ASMN1; SMN2LMNAGAA | |
| SCHEMBL28657460 | 0.87 | GAA (0.60) | MEN1KMT2ASMN1; SMN2LMNAGAA | |
| SCHEMBL28659168 | 0.85 | LMNA (0.61) | MEN1KMT2ASMN1; SMN2LMNAGAA | |
| SCHEMBL1633208 | 0.84 | CXCR4 (0.63) | MEN1KMT2ASMN1; SMN2LMNAGAA | |
| SCHEMBL28659351 | 0.84 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2LMNAGAA | |
| SCHEMBL28651416 | 0.83 | SMARCA2 (0.72) | MEN1KMT2ASMN1; SMN2LMNAGAA | |
| SCHEMBL28654462 | 0.83 | TP53 (0.55) | MEN1KMT2ASMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651365-B | 3-methylpyrido [1,2-a ] pyrimidone derivative containing 1- ((4-substituted benzyl) oxy) and application thereof | 贵州大学 | 2021-11-16 | — | — | CN | disclosed |