Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2199424 | 0.85 | BACE1 (0.48) | BACE1ESR2ALOX5HSD17B10ALDH1A1 | |
| SCHEMBL1513493 | 0.84 | BACE1 (0.52) | BACE1ESR2ALOX5HSD17B10ALDH1A1 | |
| SCHEMBL10439399 | 0.83 | BACE1 (0.50) | BACE1ESR2ALOX5HSD17B10ALDH1A1 | |
| SCHEMBL11499314 | 0.83 | BACE1 (0.44) | BACE1ESR2ALOX5HSD17B10ALDH1A1 | |
| SCHEMBL6423564 | 0.83 | ESR2 (0.53) | BACE1ESR2ALOX5HSD17B10ALDH1A1 | |
| SCHEMBL11802995 | 0.81 | ESR1 (0.46) | ESR2HSD17B10ALDH1A1HPGDMAPT | |
| SCHEMBL4954510 | 0.80 | CA12 (0.52) | CA12CA9MAPTCNR1ALOX15 | |
| SCHEMBL30335040 | 0.79 | ALOX5 (0.44) | BACE1ESR2ALOX5HSD17B10ALDH1A1 | |
| SCHEMBL30669867 | 0.79 | BACE1 (0.56) | BACE1ESR2ALOX5HSD17B10ALDH1A1 | |
| SCHEMBL79394 | 0.79 | BACE1 (0.56) | BACE1ESR2ALOX5HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111875557-B | Thiazole derivative and synthesis method thereof | 南通大学 | 2023-06-02 | — | — | CN | claimed |
| CN-111892527-B | Indole derivatives and synthesis method thereof | 南通大学 | 2022-06-28 | — | — | CN | claimed |
| CN-111892527-A | Indole derivatives and synthesis method thereof | 南通大学 | 2020-11-06 | — | — | CN | claimed |
| CN-111875557-A | Thiazole derivative and synthesis method thereof | 南通大学 | 2020-11-03 | — | — | CN | claimed |
| CN-111875557-B | Thiazole derivative and synthesis method thereof | 南通大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-111875557-B | Thiazole derivative and synthesis method thereof | 南通大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-111892527-B | Indole derivatives and synthesis method thereof | 南通大学 | 2022-06-28 | — | — | CN | disclosed |
| CN-111892527-B | Indole derivatives and synthesis method thereof | 南通大学 | 2022-06-28 | — | — | CN | disclosed |
| CN-111892527-A | Indole derivatives and synthesis method thereof | 南通大学 | 2020-11-06 | — | — | CN | disclosed |
| CN-111892527-A | Indole derivatives and synthesis method thereof | 南通大学 | 2020-11-06 | — | — | CN | disclosed |
| CN-111875557-A | Thiazole derivative and synthesis method thereof | 南通大学 | 2020-11-03 | — | — | CN | disclosed |
| CN-111875557-A | Thiazole derivative and synthesis method thereof | 南通大学 | 2020-11-03 | — | — | CN | disclosed |
| US-7713449-B2 | Polymer electrolytic material, polymer electrolytic part, membrane electrode assembly, and polymer electrolyte fuel cell | TORAY INDUSTRIES, INC. (JP) | 2010-05-11 | — | — | US | disclosed |
| CN-100364160-C | Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell | TORAY INDUSTRIES (JP) | 2008-01-23 | — | — | CN | disclosed |
| US-20060180796-A1 | Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell | TORAY INDUSTRIES, INC. (JP) | 2006-08-17 | — | — | US | disclosed |
| EP-1619735-A1 | POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE PART, MEMBRANE ELECTRODE COMPOSITE AND POLYMER ELECTROLYTE TYPE FUEL CELL | TORAY INDUSTRIES, INC. (JP) | 2006-01-25 | — | — | EP | disclosed |
| EP-1392673-A2 | 1,3-DIHYDROXYBENZENE DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002096901-A2 | 1,3-DIHYDROXYBENZENE DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-05 | — | — | WO | disclosed |