SCHEMBL6423564

SCHEMBL6423564

Cc1ccc(-c2ccccc2)c(O)c1C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.53
HDAC4 P56524 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
BACE1 P56817 2/20 0.44
ELANE P08246 1/20 0.44
ALOX5 P09917 1/20 0.43
POLB P06746 1/20 0.43
RECQL P46063 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALDH1A1 P00352 3/20 0.43
HPGD P15428 1/20 0.43
BCL2L1 Q07817 1/20 0.43
HSD17B10 Q99714 1/20 0.43
PDCD1 Q15116 1/20 0.42
CD274 Q9NZQ7 1/20 0.42
HNF4A P41235 1/20 0.42
CYP2A6 P11509 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10617137 0.84 ESR2 (0.55) ESR2HDAC4HDAC2HDAC8HDAC6
Methane SCHEMBL28025030 0.83 ESR2 (0.53) ESR2HDAC4HDAC2HDAC8HDAC6
SCHEMBL9469704 0.83 ESR2 (0.53) ESR2HDAC4HDAC2HDAC8HDAC6
SCHEMBL2865463 0.83 BACE1 (0.50) ESR2HDAC4HDAC2HDAC8HDAC6
SCHEMBL8067080 0.83 TDP2 (0.40) ESR2BACE1ELANEALOX5POLB
SCHEMBL1513737 0.83 ESR2 (0.53) ESR2HDAC4HDAC2HDAC8HDAC6
SCHEMBL339799 0.81 TDP2 (0.44) ESR2ELANEPOLBRECQLNPSR1
SCHEMBL4473038 0.80 TDP2 (0.46) ESR2BACE1ALOX5ALDH1A1PDCD1
SCHEMBL2400343 0.79 ESR2 (0.48) ESR2BACE1ALOX5POLBALDH1A1
SCHEMBL30804714 0.79 ESR2 (0.48) ESR2BACE1ALOX5POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1494995-A1 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS Wella Aktiengesellschaft (DE) 2005-01-12 EP claimed
WO-2003087034-A1 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS WELLA AKTIENGESELLSCHAFT (DE) 2003-10-23 WO claimed
US-12503480-B2 Cyclic phosphazene compound having oxaphosphorin ring-containing structure FUSHIMI PHARMACEUTICAL CO., LTD. (JP) 2025-12-23 US disclosed
CN-118204116-A Catalyst for preparing p-cresol by toluene shape-selective hydroxylation and preparation method and application thereof 中国科学院大连化学物理研究所 2024-06-18 CN disclosed
CN-117443446-A Preparation method of catalyst for preparing p-cresol from toluene and preparation method of p-cresol 中国天辰工程有限公司 2024-01-26 CN disclosed
CN-117443445-A Preparation method of catalyst for preparing m-cresol from toluene and preparation method of m-cresol 中国天辰工程有限公司 2024-01-26 CN disclosed
US-20230339994-A1 CYCLIC PHOSPHAZENE COMPOUND HAVING OXAPHOSPHORIN RING-CONTAINING STRUCTURE FUSHIMI PHARMACEUTICAL CO., LTD. (JP) 2023-10-26 US disclosed
EP-4202013-A1 CYCLIC PHOSPHAZENE COMPOUND HAVING OXAPHOSPHORIN RING-CONTAINING STRUCTURE Fushimi Pharmaceutical Co., Ltd. (JP) 2023-06-28 EP disclosed
CN-116194552-A Cyclic phosphazene compounds having oxaphosphaphenanthrene-containing ring structure 株式会社伏见制药所 2023-05-30 CN disclosed
CN-110683940-B Method for converting dibenzo [ c, e ] [1,2] oxathiane-6-oxide compound 中国科学院成都生物研究所 2022-07-01 CN disclosed
CN-108430970-B Bisphenol compound and aromatic polycarbonate 本州化学工业株式会社 2022-03-11 CN disclosed
CN-108430970-A Bisphenol compound and aromatic copolycarbonate 本州化学工业株式会社 2018-08-21 CN disclosed
CN-106000442-B Ortho-chlorotolu'ene hydrolyzes the preparation method of metacresol special-purpose catalyst processed 江苏钟腾化工有限公司 2018-07-10 CN disclosed
CN-106000442-A Preparation method of catalyst specially used for preparing m-cresol by hydrolyzing o-chlorotoluene 江苏钟腾化工有限公司 2016-10-12 CN disclosed
CN-106008170-A New green process for preparing high-purity m-cresol 江苏钟腾化工有限公司 2016-10-12 CN disclosed
CN-105906481-A P-cresol preparation method and equipment 金能科技股份有限公司 2016-08-31 CN disclosed
CN-103288602-B Method for preparing p-cresol from anisole and preparation method of used catalyst thereof DALIAN CHEMICAL PHYSICS INST 2014-12-10 CN disclosed
CN-103288602-A Method for preparing p-cresol from anisole and preparation method of used catalyst thereof DALIAN CHEMICAL PHYSICS INST 2013-09-11 CN disclosed
CN-102807475-A Method for preparing orthocresol and metacresol ANHUI HAIHUA SCIENCE & TECHNOLOGY CO LTD 2012-12-05 CN disclosed
CN-101107388-B Method for producing plated resin formed article DAICEL POLYMER LTD 2012-06-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230339994-A1 CYCLIC PHOSPHAZENE COMPOUND HAVING OXAPHOSPHORIN RING-CONTAINING STRUCTURE PFAS, PHOSPHO1, PAF1 ESR2 1224/4885HDAC4 2824/4885HDAC2 1570/4885
US-12503480-B2 Cyclic phosphazene compound having oxaphosphorin ring-containing structure PFAS, PHOSPHO1, PAF1 ESR2 1224/4885HDAC4 2824/4885HDAC2 1570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.