SCHEMBL2865464

SCHEMBL2865464

CCCC(Br)OC(=O)C(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 6/20 0.50
CHRM3 P20309 6/20 0.50
KLK7 P49862 6/20 0.50
CHRM2 P08172 5/20 0.50
CHRM4 P08173 5/20 0.50
CYP1A2 P05177 2/20 0.48
CYP2D6 P10635 2/20 0.48
LMNA P02545 1/20 0.48
CYP3A4 P08684 3/20 0.47
ALDH1A1 P00352 3/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
POLB P06746 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.44
KMT2A Q03164 1/20 0.43
CHRM5 P08912 2/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2859451 0.81 KLK7 (0.50) CHRM1CHRM3KLK7CHRM2CHRM4
SCHEMBL359759 0.81 KLK7 (0.57) CHRM1CHRM3KLK7CHRM2CHRM4
SCHEMBL359760 0.81 KLK7 (0.57) CHRM1CHRM3KLK7CHRM2CHRM4
SCHEMBL2864140 0.81 KLK7 (0.50) CHRM1CHRM3KLK7CHRM2CHRM4
SCHEMBL2859574 0.78 KLK7 (0.57) CHRM1CHRM3KLK7CHRM2CHRM4
SCHEMBL360674 0.75 KLK7 (0.59) CHRM1CHRM3KLK7CHRM2CHRM4
SCHEMBL360673 0.75 KLK7 (0.59) CHRM1CHRM3KLK7CHRM2CHRM4
SCHEMBL6600103 0.74 LMNA (0.43) CHRM1CHRM3KLK7CHRM2CYP1A2
SCHEMBL29356505 0.74 LMNA (0.43) CHRM1CHRM3KLK7CHRM2CYP1A2
SCHEMBL360679 0.74 KLK7 (0.66) CHRM1CHRM3KLK7CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1795581-B1 LUBRICATING OIL COMPOSITION CONTAINING ACRYLIC POLYMER KURARAY CO (JP) 2018-09-19 EP disclosed
US-7718588-B2 Lubricating oil additive containing acrylic polymer and lubricating oil compositions KURARAY CO., LTD. (JP) 2010-05-18 US disclosed
US-20080058234-A1 Lubricating Oil Additive Containing Acrylic Polymer and Lubricating Oil Compositions KURARAY CO., LTD. (JP) 2008-03-06 US disclosed
EP-1795581-A1 LUBRICATING OIL ADDITIVE CONTAINING ACRYLIC POLYMER AND LUBRICATING OIL COMPOSITIONS KURARAY CO., LTD. (JP) 2007-06-13 EP disclosed